Molecular and Nanoscale Physics

Latest News

New Biomedical Facility on the Horizon

18 November 2014

Congratulations to Professor Steve Evans and Drs Kevin Critchley and Jung-uk Shim from the MNP group in Physics and Astronomy, University of Leeds, who has been awarded a joint MRC grant for Single Cell Genomics with members of the Leeds Teaching Hospitals NHS Trust.

 

A joint facility that will permit new biomedical research approaches, based on sequential isolation, manipulation, observation and eventual destructive analysis (or culture and expansion) of single cells will be generated from the funds.

The facility will focus on delivering biological insights and capabilities that are relevant to their clinical areas of expertise and excellence.

 

 




Q-Dot Paper

17 November 2014

Dr Kevin Critchley has recently had a paper published in the 'The Journal of Physical Chemistry' on the subject of Q-Dots.

The paper is titled, 'Sub-Bandgap Emission and Intraband Defect-Related Excited-State Dynamics in Colloidal CuInS2/ZnS Quantum Dots Revealed by Femtosecond Pump–Dump–Probe Spectroscopy', and has contributions from Kraatz, Booth, Whitake and Nix.

To read the paper, please click here.




Congratulations to Dr Heath!

13 November 2014

Congratulations to George Heath who successfully passed his PhD viva on 12th Nov 2014.

George’s work involved studying model lipid membrane systems mainly using the technique of atomic force microscopy. His work encompassed applications in nano-patterning of lipid bilayers, study of the critical point behaviour of model membranes, protein partitioning and diffusion in lipid membranes, polymerisation of actin on cationic lipids at sub-critical concentrations and coating theranostic microbubbles with actin layers.

His project supervisors were Dr. Simon Connell and Prof. Stephen Evans. The internal examiner was Dr. Neil Thomson and the external examiner Prof. Erik Reimhult of the Universitat for Bodenkultur, Vienna.

 




Life in Extreme Environments

12 November 2014

The Physics of Life Network and School of Physics and Astronomy hosted a two-day focused workshop on Life in Extreme Environments at Weetwood Hall yesterday.

The day included a variety of Flash Presentations, networking opportunities and a key note speech from Professor Joseph Zaccai from the Institut Laue Langevin, Grenoble. Professor Zaccai’s talk discussed ‘Dynamics and adaptation to extreme environments’ and was a great addition to the workshop.

Dr Lorna Dougan, Associate Professor in the Molecular and Nanoscale research group in the School chaired the event with assistance from Professor Steve Evans. The aim of the workshop was to highlight areas of research in the remit of Extremophiles and consider how physicists, Biologists and others could form collaborations to develop existing research.

For further information about the event, speakers and network, please click here.

 




Upcoming Winter School

3 November 2014

The Leeds EPSRC Nanoscience and Nanotechnology Facility (LENNF), Winter School is free and open to all PhD students in relevant fields at UK Universities.

It will include lectures, demonstrations and Q&A sessions about the equipment and techniques available through the facility. The School will run from 13-15th January, and accommodation will be provided and travel costs reimbursed by LENNF.

Registration closes on 24/11/2014 please contact Dr Kellye Curtis (K.S.Curtis@leeds.ac.uk) for further details and to register.

Please visit the website: http://www.engineering.leeds.ac.uk/lennf/




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23rd April 2014

Congratulations to Adam Churchman who recieved the prize for best poster at this year's IOP Conference, "Solutions in the Spring".

Adam's poster focused on, "Developing microfluidic methods of producing microbubble with an inner oil layer towards hydrophobic delivery".

This year's IOP Conference ran from 11-14th at Homerton College, Cambridge. For more details about the conference, please click here.

 

Physical Sciences and Oncology Away Day success

10th April

The School of Physics and Astronomy recently hosted a Physical Sciences and Oncology Away Day for the Faculty of MaPS. The delegate list included clinicians from the field of Oncology, it was an opportunity for both the Physical Scientists and Clinicians to get together to discuss the challenges. There were 40 delegates in total on the day.

Professor Steve Evans, Head of Group in MNP and Director of Research for the School, led the day and arranged for the following topics to be discussed:

Steve Smye gave an overall introduction to the challenges that researchers in the field are currently facing and David Buckley gave a brief talk about Imaging.

Understanding disease (Basic Sciences/Modelling), introduced by Professor Pam Jones

Diagnostics (Imaging/Sensing) presented by Mr Greg Taylor from St James Hospital

Treatment (Imaging/Delivery) by Professor Peter Selby

Vivian Cosgrove also gave a brief introduction to Radiotherapy Physics Research

The day comprised of small group discussions and workshops, looking at refining the challenges, developing solutions and finally feeding back to the rest of the group.

The intention of the day was to develop new collaborations, we are pleased to say that a very positive outcome was established and we hope to be taking these new ideas forward very soon.

Thank you to everyone who was involved in the organisation of the day and for those delegates who took part in what we can confidently say was a very successful day.

 

Megan Hughes wins best presentation at recent PG Symposium

4th April 2014

Congratulations to Miss Megan Hughes on being awarded the best presentation at this years Postrgraduate Symposium, held on Tuesday 1st April 2014.

Megan is part of the Dougan group in Molecular & Nanoscale Physics and is currently focusing her research on physics proteins, which are biological molecules with very important functions in the cell. These molecules have unique 3D shapes and Megan is interested in the importance of the forces that hold this 3D shape together.

To see Megan's prize winning presentation, please click here

Victoria Mico wins best poster prize at recent PG Symposium

4th April 2014

Congratulations to Miss Victoria Mico for winning the best poster prize at this years Annual Postgraduate Symposium.

The poster focused on 'Engineering lipid oil nano-droplets for hydrophobic drug delivery', and included input from Dr Sally Peyman and Professor Stephen Evans. To take a look at the winning poster, please click here

The PG Symposium is held every year at University of Leeds and is a great opportunity for PG in Physics and Astronomy to showcase their research in particular areas.

1st April 2014

Registration Opens for this years Microbubble Symposium

Registration for the Annual Microbubble Symposium opens today, to register, please visit our Microbubble webpage

For a full list of speakers and further details about the Symposium, please click here

This is the fourth year Leeds Microbubble Consortium have hosted the Symposium, for details about previous years, please click here

PhD position: New single molecule techniques for understanding protein-DNA interactions

28th March

DEADLINE: 1st MAY 2014

BACKGROUND

Protein-DNA interactions are central to many major cellular processes, including transcription, replication, and packaging of DNA into chromatin. However, we still know very little about how proteins interact physically with DNA. Without this basic knowledge we will be unable to understand many of the processes underpinning nucleic acid metabolism. New approaches are therefore required to probe directly how proteins bind to and manipulate DNA.

THE PROJECT

The project will exploit novel single molecule approaches to examine protein-DNA complexes with unprecedented molecular resolution. The ability to control, manipulate and interrogate single molecules will provide powerful insight into the function of these systems and, ultimately, will help us to understand the processes that underpin all aspects of nucleic acid metabolism. The project will make use of novel direct physical approaches to characterise the stability, flexibility and function of protein-DNA complexes (force clamp AFM) and will benefit from the unique collection of skills and experience of the research team.

The project is a collaboration between Dr Lorna Dougan in Physics at Leeds and Prof Peter McGlynn  in Biology at York.

THE NETWORK

This project forms part of a new White Rose studentship network “New single molecule techniques for understanding the physics of living systems” and is made up of a team of collaborators from the Universities of Sheffield, Leeds and York. The goal of the network is to develop new physical approaches to answer biological questions and new ways for working collaboratively across the physics-life science interface to maximise the impact of these approaches.

If you are interested, please contact Dr Lorna Dougan - l.dougan@leeds.ac.uk

 

Registration for the Microbubble Symposium on April 1st

24th March

Registration will open for the Annual Microbubble Symposium on Tuesday 1st April.

This year we have another impressive line up of high profile speakers from the Microbubble field, including:

Valeria Garbin, Ian Miller, Jose Manuel Gordillo Arias de Saavedra, Abraham Lee, T.G.Leighton, Michiel Postema, Neil Thomson, Alexander Klibanov and Juergen Willmann

The Symposium will run over 2 days, from 1pm on Monday 14th July to Tuesday 15th July.

Full details of registration costs will be available on the Microbubble website from 1st April.

Leeds' Academic's speak at LCMB conference in India

7 March 2014

Professor Stephen Evans and Professor Richard Bushy recently attended the 'Light in Chemistry, Materials and Biology' in Kharagpur, India. Both were invited to speak at the conference and Richard was announced as the guest of honour.

The conference ran from 24th to 25th February 2014 at the Indian Institute of Technology in Kharagpur.

Speakers Announced for Forthcoming Microbubble Symposium

13 February 2014

We are pleased to confirm the following people will be speaking at this year's...

We are pleased to confirm the following people will be speaking at this year's Microbubble Symposium at Weetwood Hall, 14-15 July:

Valeria Garbin - Imperial College London

Jose Manuel Gordillo Arias de Saavedra - Sevilla University

Alexander Klibanov - University of Virginia

Abraham Lee - UC Irvine

T.G.Leighton - University of Southampton

Michiel Postema - University of Bergen

Ronald Roy - University of Oxford

Neil Thomson - University of Leeds

Juergen Karl Willmann - Stanford University

Registration will open on 1st April, further details will be listed on our Microbubble page, here

Leeds Microbubble Group attend 19th European Symposium on Ultrasound Contrast Imaging

23-24th January 2014

Members of the Leeds Microbubble Group attended the 20th European Symposium on Ultrasound Contrast Imaging in Rotterdam.

Sally Peyman produced the following poster about Microbubbles as stable drug-loadable structures toward targeted, triggered drug delivery, which can be viewed here.

For more information please click here.

Leeds Microbubble Group feature in Soft Matter blog

Issue 5, 2014

'Self-assembly of actin scaffolds on lipid microbubbles.' Please use the links below to take a further look at the paper and also the front cover of the blog.

Soft Matter Hot Papers 2014

Soft Matter Blog

Front Cover

Congratulations to those involved: George R. Heath, Radwa H. Abou-Saleh, Sally A. Peyman, Benjamin R.G. Johnson, Simon D. Connell and Stephen D. Evans

Microbubble Symposium 2013

The Annual Leeds Microbubble Symposium was held in June 2013 this year. Guest speakers included a number of world leaders in Microbubble research. The list of speaker is as follows:

Mark Borden, Eleanor Stride, Mangala Srinivas ,Michael Versluis, James McLaughlan, Oliver Couture, Georg Schmitz, Georg Feichtinger, Lori Bridal, Alexander Kilbanov, Klazina Koiiman, Heleen Dewitte, Jeff Bamber, Sandra Meyer and Paul Sidhu.

More details about the Annual Symposium can be found here.

14/07/13: Epigem and University of Leeds unveil first Microbubble Instrument - The HORIZON - for more information, click here